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Shunya Yagi

PhD Candidate


University of British Columbia

Discovery (Biological & Genetic Mechanisms)

Overall objective of my research project will focus on sex difference and the effect of estrogens on adult neurogenesis and hippocampus-related cognition in rodents. Firstly, I am looking at sex differences in cognitive flexibility and the effect of estrogens on the ability of memory encoding with examining neural plasticity and learning related cell signaling pathways. Secondly, I am looking at sex differences and the role of estrogens on adult-born neurons in the dentate gyrus of hippocampus. Thirdly, I am interested in sex-dependent, age-related cognitive decline in rats examining the ability for cognitive flexibility and the capacity of neural plasticity in aged males and females.

Area of Research Expertise
Sex differences; Estrogens; Cognitive flexibility; Memory; Learning