Sex and gender impact disease risk, manifestation, and outcomes in a variety of ways. However, females were excluded from clinical and pre-clinical studies for decades due to concerns over reproductive harm in humans and “complicated” hormone cycles in animals. This exclusion has resulted in a significant gap in our knowledge of health and disease in women and gender diverse individuals.
In addition to the research conducted by our members, the WHRC does it's own research to help us facilitate deeper integration of sex and gender-based anlysis. Click below and check back soon for more information on these projects.
Assessing SGBA Adoption in CIHR-Funded Research
Sex and gender impact disease risk, manifestation, and outcomes in a variety of ways. However, females were excluded from clinical and pre-clinical studies for decades due to concerns over reproductive harm in humans and “complicated” hormone cycles in animals. This exclusion has resulted in a significant gap in our knowledge of health and disease in women and gender diverse individuals.
To bridge this gap, the Canadian Institutes of Health Research (CIHR), the primary funding body for health research in Canada, recommended and later mandated the adoption of Sex- and Gender-Based Analysis (SGBA) in research methodology. Thus, researchers applying for funding are now required to discuss how sex and/or gender play a role in their research and how they plan to analyze these variables. This project sought to examine whether CIHR’s changing policies around SGBA increased the mentioning of sex or gender, female-specific health, or 2S/LGBTQIA+ health in the abstracts of successful CIHR grant applications from 2009-2020.
We found that less than 3% of funded research abstracts mentioned sex or gender, less than 6% investigated female-specific outcomes, and just 0.35% focused on the 2S/LGBTQIA+ community. Funded proposal abstracts mentioning sex or 2S/LGBTQIA+ health increased slightly over time, whereas abstracts mentioning gender or female-specific health did not change. The percentages of overall funding allocated for sex, gender, female-specific health, and 2S/LGBTQIA+ health research largely mirrored these trends. Our results suggest that more work needs to be done to increase the adoption of SGBA in health research. Individual researchers, funding agencies, and publishers all play in integral role in closing the women’s health knowledge gap and advancing equity in health research.
Read our paper preprint on bioRxiv and a blog post (comming soon) summarizing our findings.
Figure A: An infographic depicting the change in percentage of grants and funding between 2009 and 2020 for awarded Canadian institutes of Health Research (CIHR) grants for the different categories. The change in percentage (%) of grants (A) and funding amount (B) in the years 2009 and 2020 that “omitted” mention of sex and gender in their grant abstracts or mentioned female-specific health, female-specific health not including cancer based grants, sex, gender, or 2S/LGBTQIA+ health.
SGBA Pathways Project
Are you a trainee who includes (or wants to include) Sex- and Gender-Based Analysis (SGBA) in your research?
The SGBA Working Group at the Women’s Health Research Cluster has partnered with the Vascular Dynamics Lab at McMaster University to launch a new study on SGBA pathways! We’re interested in the paths trainees take to begin including SGBA in their research, and the barriers and facilitators they come across.
Considering sex and gender differences in health research is necessary to adequately prevent, diagnose and treat individuals equally. Unfortunately SGBA is often left out of research, which leads to health disparities. Uncovering the common facilitators and barriers trainees experience will help us to determine how we might enable more young professionals to incorporate SGBA in their research.
Jennifer Williams, Jessica Stewart and Katherine Moore are currently working on this project. If you’re a trainee, stay tuned by subscribing to our newsletter and following us on social media. We’ll notify you when recruitment for this study begins!